International Journal of Biochemistry and Biotechnology

ISSN 2169-3048

International Journal of Biochemistry and Biotechnology ISSN 2169-3048 Vol. 12 (1), pp. 001-006, January, 2023. © International Scholars Journals

Full Length Research Paper

Enhanced Phagocytosis and Antibody Production by Tinospora cordifolia - A new dimension in Immunomodulation

M. S. Ranjith1*, A.J.A. Ranjitsingh2, S. Gokul Shankar3, G. S. Vijayalaksmi5, K. Deepa5 and Harcharan Singh Sidhu1

1Microbiology Unit, AIMST University, Kedah, Malaysia.

2Department of Advanced Zoology and Biotechnology, Sri Paramakalyani College, Alwarkurichi, India.

3R and D Center, Cholayil Private Limited, Chennai, India.

4Sri Paramakalyani Center for Environmental Sciences, M.S. University, Tirunelveli, India.

5Anatomy Unit, AIMST University, Kedah, Malaysia.

Accepted 18 December, 2022

Abstract

Tinospora cordifolia (guduchi) is a widely used shrub in ayurvedic systems of medicine known to possess immunomodulatory properties. In the present study the aqueous extract of T. cordifolia was found to enhance phagocytosis in vitro. The aqueous and ethanolic extracts also induced an increase in antibody production in vivo.

Key words: Immunomodulation, phagocytosis assay, Tinospora cordifolia.

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K. Deepa and Harcharan Singh Sidhu on Google Scholar K. Deepa and Harcharan Singh Sidhu on Pubmed A.J.A. Ranjitsingh on Google Scholar A.J.A. Ranjitsingh on Pubmed G. S. Vijayalaksmi on Google Scholar G. S. Vijayalaksmi on Pubmed S. Gokul Shankar on Google Scholar S. Gokul Shankar on Pubmed M. S. Ranjith* on Google Scholar M. S. Ranjith* on Pubmed