ISSN 2756-3413
African Journal of Virology Research ISSN 2756-3413 Vol. 18 (6), pp. 001-004, June, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Antimicrobial Resistance of Pseudomonas aeruginosa in Cameroon: A Meta-Analytic Review
Yves Le Grand Napa Tchuedji1, Hortense Gonsu Kamga2,3, Emilia Lyonga Mbamyah2, Anicette Chafa Betbeui3, Francois-Xavier Etoa1 and Yap BoumII4,5
1Department of Microbiology, Laboratory of Microbiology, University of Yaoundé I, Yaoundé, Cameroon.
2Department of Microbiology, Parasitology, Haematology and InfectiousDiseases, Faculty of Medicine and Biomedical
Sciences, University of Yaounde I, Yaoundé, Cameroon
3Laboratory of Bacteriology, UniversityTeachingHospital, Yaounde, Cameroon.
4Epicenter Africa Research Centre, Yaoundé, Cameroon
Accepted 10 November, 2022
Background: Pseudomonas aeruginosa is a non-fermentative bacteria which present a rapid increase in the rates of infections across the world. Pseudomonas aeruginosa ranks third among the resistant bacteria responsible for nosocomial infections. Aim: To assess the distribution and evolution of resistance of Pseudomonas aeruginosa in Cameroon. Methods: We carried out a systematic review of the research publications that determined the resistance phenotypes of Pseudomonas aeruginosa in Cameroon. A meta-analysis of the data was carried out to synthesize the data on resistance phenotypes, their distribution and their evolution in Cameroon. Results: A considerable increase in resistance to ceftazidime, aztreonam, gentamycin and tobramycin between 2005 and 2011 was observed. In addition, an increase in resistance to imipenem was noted between 2011 and 2013. The city of Douala has a high frequency of Pseudomonas aeruginosa followed by Buea and Yaounde. Conclusion: Pseudomonas aeruginosa has a high frequency and resistance to several antibiotics in Cameroon. There is a need to continue surveillance in several hospitals and in several regions of Cameroon in order to implement policies and measures to fight infections and antibiotic resistance.
Keywords: Pseudomonas aeruginosa, resistance, antibiotics, epidemiology, clinical isolates.