ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 9 (10), pp. 001-006, October, 2020. © International Scholars Journals
Full Length Research Paper
Elemental analysis and Anti-microbial potentials of the leaf extract of Cassia arereh Del
Adeyanju Olusola1*, Olajide Olutayo2, Afolayan Michael2, Fatokun Olakunle2, Edah A. O3
1Department of Chemistry, University of Jos, P.M.B 2084, Jos, Nigeria.
2Chemistry Advanced Laboratory, Sheda Science and Technology Complex, P.M.B. 186, Garki, Abuja.
3Department of Pharmaceutical Chemistry, University of Jos, P.M.B 2084, Jos, Nigeria.
Accepted 21 July, 2020
Abstract
The phytochemical analysis, elemental analysis, antimicrobial activities and the minimum inhibitory concentration (MIC) of aqueous and ethanolic extracts of the leaves of Cassia arereh Del. were carried out. Phytochemical investigation revealed the presence of several bioactive compounds such as alkaloids, flavonoids, anthraquinones, saponins, glycosides, tannins, carbohydrates and terpenes. Elemental analysis revealed the presence of calcium (Ca), phosphorus (P), Manganese (Mg), Manganese (Mn), Iron (Fe), Copper (Cu) and Zinc (Zn). Manganese was present at a higher concentration (11.50 µg/g) followed by Zinc (3.35 µg/g). Antimicrobial studies showed that the ethanolic extract had considerable inhibitory activity against Staphylococcus aureus, Streptococcus pyogen, Salmonella typhi, Shigella dysentery and Eschenchia coli. Ethanolic extract had higher zone of inhibition (32 mm) against salmonella typhi at (0.5 µg/ml) with minimum inhibitory concentration (MIC) value of 8 x 102 µg/ml. The MIC ranges from 4 x 102 µg/ml to 5 x 104 µg/ml for other bacteria.
Keywords: Cassia arereh, Caesalpiniceae, Medicinal plant, phytochemical, antimicrobial activity.