ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 14 (2), pp. 001-004, February, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
In Vitro Evaluation of Antiparasitic Activities of Selected Medicinal Plants Against Trypanosoma evansi
Adeiza, A. A.*, Maikai, V. A. and Hassan, F. B.
College of Agriculture and Animal Science, Ahmadu Bello University, P.M.B. 2134, Mando Road, Kaduna, Nigeria.
Accepted 15 November, 2024
In an attempt to search for new eco-friendly trypanocidal drugs, water and methanol extracts were prepared from three medicinal plants used by herbalists in Nigeria for the treatment of malaria and other ailments. The different portions of the extracts were incubated at various concentrations, 2, 4, 8, 10 mg/ml with Trypanosoma evansi. The results revealed that Khaya senegalensis and Anonna senegalensis were able to immobilize the parasites at 10 mg/ml while Prosopis africana did not show any activity. Phytochemical profile of the plants showed the presence of alkaloids, flavonoids, tannins, saponnins and cardiac glycosides. The results obtained with these crude extracts showed that these plants are potential sources of trypanocidal drugs/chemical leads.
Key words: Antitrypanosomal activity, Khaya senegalensis, Anonna senegalensis, Prosopis africana, Trypanosoma evansi.