International Journal of Pharmacy and Pharmacology

ISSN 2326-7267

International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 9 (1), pp. 001-005, January, 2020. © International Scholars Journals

Full Length Research Paper

Comparing different sedation medications using generalized estimating equations approach

M. A. Cengiz1*, T.    enel1, Y. Terzi1, N. Murat1 and N. Sava 2

1Department of Statistics, Ondokuz Mayıs University, Samsun, Turkey.

2Department of Mathematics, Erzincan University, Erzincan, Turkey.

Accepted 08 November, 2019

Abstract

Generalized estimating equations (GEE) provide an applicable approach to modelling repeated and clustered data that are often encountered in medical application. This approach is very useful especially when response variables are correlated and categorical, covariates are time-depended, there are a large number explanatory variables and missing data. In this study, using this approach we focus on modelling repeated sedation measurements obtained during magnetic resonance imaging (MRI) and computerized tomography (CT) for children.

Key words: Sedation, midazolam, generalized linear models.