Isolation and characterization of a new chalcone from the leaves of Heteropyxis natalensis

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 7 (10), pp. 001-005, October, 2018. © International Scholars Journals

Full Length Research paper

Isolation and characterization of a new chalcone from the leaves of Heteropyxis natalensis

Adesanwo, J. K.¹*, Shode, F. O.², Aiyelaagbe, O.³, Oyede, R. T.² and Baijnath, H.⁴

¹Chemistry Department, Obafemi Awolowo University, Ile-Ife Osun State, Nigeria

²School of Chemistry, Westville Campus, University of KwaZulu-Natal, P/Bag X54001, Durban, South Africa.

³Chemistry Department University of Ibadan, Nigeria.

⁴School of Conservation and Biological Sciences, Westville Campus, University of KwaZulu-Natal, P/Bag X54001, Durban, South Africa.

Accepted 16 July, 2018

Abstract

Chromatographic analysis of the defatted dichloromethane extract of the leaves of Heteropyxis natalensis afforded the isolation of (E)-1-(2’,4’-dihydroxy, 5’-methoxy, 3’-methylphenyl) -3-phenylprop-2-en-1-one (R1 = Me; R2 = OH; R3 = OMe; R4 = H) a chalcone. The structure of this compound was established by its spectroscopic data-1D, 2D-NMR, EIMS and HR-EIMS.

Key words: Chalcones, Heteropyxis natalensis, heteropyxidaceae, flavone.

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