ISSN 2756-3707
International Journal of Histology and Cytology ISSN 2756-3707 Vol. 13 (2), pp. 001-006, February, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Genomic Characteristics and Diversity of Iranian Indigenous Goats
B. Mahmoudi1*, M. Sh. Babayev2, F. Hayeri Khiavi1, A. Pourhosein1 and M. Daliri3
1Islamic Azad University, Meshkinshahr Branch, Meshkinshahr, Ardabil, Iran.
2Department of genetic, Faculty of Biology, Baku State University, Baku, Azerbijan.
3Department of Animal Science, Genetic Engineering and Biotechnology Institute, Tehran, Iran.
Accepted 7 November, 2024
Investigation of genetic relationship among populations was traditionally based on the analysis of allele frequencies at different loci. The aim of this study was to analyze, the genetic diversity and variability of three native Iranian goat populations (Raeini, Korki Jonub Khorasan and Lori) through the use of 13 microsatellite markers. The 13 tested loci were all polymorphic in the three goat populations. Within the 13 polymorphic loci, allele frequencies, number of effective alleles (Ne), heterozygosity (He), polymorphism information content (PIC) and Nei's standard genetic distance (D) were calculated, and UPGMA phylogenetic tree was constructed based on allele frequencies. The average number of alleles was 7.57, ranging from 3 to 13 at the 13 assessed loci. The average values of Ne, He and PIC of all loci were 5.14, 0.797 and 0.757 respectively. Korki Jonub Khorasan showed the highest mean number of alleles (8.15), while the highest value for polymorphic information content was observed for Raeini population (0.78). Tests of genotype frequencies for deviation from the Hardy-Weinberg equilibrium (HWE), had been tested in the level of probability (p<0.005). A UPGMA diagram based on Nei's standard genetic distances, yielded relationships between populations that agreed with what is known about their origin, history and geographical distribution.
Key words: Hardy-Weinberg equilibrium (HWE), goat, diversity, microsatellite.