ISSN 2756-3413
African Journal of Virology Research ISSN 2756-3413 Vol. 18 (9), pp. 001-007, September, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Prevalence of dengue fever in non-malaria fever syndromes at Angré University Hospital, Abidjan
Kouamé Yao Gilles Privat1, Adjogoua Valery Edgar3, Guina Denise A. Blassonny1;2, Cablan Mian N'dede Arsher 1;2, Boka Arthur Dreyfus1 , Lathro Joseph Serge1;2, Touré Aissata Epse Kourouma1 ,N’djomon Aimé1, Loukou Yao Guillaume 1;2, Kacou N'douba Adele 4, Nanga Yesse Zinzendorf 1; 2
1National Public Health Laboratory (NPHL), Abidjan
2Department of Bacteriology-Virology, Faculty of Pharmaceutical and Biological Sciences, Abidjan
3Institut Pasteur of Côte d'Ivoire.
4Medical Biology Laboratories, Angré University Hospital
Abstract
Received 02 September, 2025; Revised 09 September, 2025; Accepted 10 September, 2025; Published xxxx
Introduction: Côte d'Ivoire has an ecology favourable to arthropods and reports a high burden of acute febrile illnesses. However, the contribution of arbovirus infections to the burden of acute febrile illnesses is poorly understood. Given this situation, the present study was conducted to determine the level of dengue circulation in non-malaria febrile syndromes. Method: This prospective study was conducted from June to December 2021. Serum samples were collected from non-malaria fever patients after obtaining their consent at the Angré University Hospital laboratory. Dengue virus detection was performed using several biological diagnostic tools: serological tests, antigen tests and RT-PCR. Results: A total of 72 febrile patients agreed to participate in the study, with a majority of male patients (51%) and a predominance of patients aged between 21 and 31 (25%). There was a high level of ignorance about dengue fever (74%) and more than 98% had never seen a case among their friends and family. In addition, 78% said they did not use impregnated mosquito nets and 87.5% reported regular exposure to mosquito bites, indicating a high level of vulnerability. Biologically, a seroprevalence of 17% (12/72) was detected, solely through the presence of IgG antibodies, suggesting past infections. However, no NS1 antigen or IgM antibodies were detected, and RT-PCR was negative for all samples. Conclusion: Dengue circulates at low levels among non-malaria fever syndromes, with no viraemia detected at the time of the study.
Keywords: Dengue, febrile syndromes, thick smear negative, NS1 antigen, RT-PCR.