ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 6 (11), pp. 001-005, November, 2017. © International Scholars Journals
Full Length Research Paper
A comparison study of Morven gold and Tander virginia cigarettes with respect to its spasmogenic, spasmolytic and chemical screening
Naveed Ullah1*, Mir Azam Khan1, Afzal Haq Asif2, Habib Ahmad3, Taimur Khan4, Taous Khan5 and Waqar Ahmad1
1Department of Pharmacy, University of Malakand, Chakdara Pakistan.
2Department of Pharmacology, Frontier Medical College, Abbottabad Pakistan.
3Department of Genetics, Hazara University, Mansehra Pakistan.
4Department of Psychiatry, Lady Reading Hospital Peshawar, Pakistan
5Department of Pharmacy, Comsats Institute of Information & Technology, Abbottabad, Pakistan
Accepted 17 March, 2017
Abstract
The ethanolic extracts derived from cigarettes (Morven gold and Tander virginia) were screened for chemicals, spasmogenic and spasmolytic activities. M. gold extract showed a strong relaxant activity that is 70% against KCl induced contractions while T. virginia was found to have a mild spasmolytic activity of (06%). Furthermore, a moderate spasmogenic effect of M. gold had being measured, while no measurable spasmogenic activity has been shown by the T. virginia. It can be concluded from the current study that Morven gold has a strong spamsmogenic and spasmolytic activity, while the Tander is not found to be so efficient in either case. The chemicals found in sufficient quantity in both the extracts were tannins, saponin and glycosides. Minute quantity of carbohydrates were also been noted in M. gold . The presence of alkaloids were also been noted in excess quantity in T. virginia and less amount in M. gold. Further studies are necessary to elucidate its exact mechanism of action.
Key words: Spasmogenic, spasmolytic, chemical screening, Morven gold, Tander virginia.