ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 6 (9), pp. 001-006, September, 2017. © International Scholars Journals
Full Length Research Paper
Sex based pharmacological treatment in patients with metabolic syndrome: Findings from the Isfahan healthy heart program
Mojgan Gharipour1*, Roya Kelishadi2, Nafiseh Toghianifar2, Mahsa Mackie3, Mehrdad Yazdani2, Fatemeh Noori4 and Nizal Sarrafzadegan2
1Department of Biochemistry, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
2Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
3Centre for Neuroscience, University of Alberta, Canada.
4Statistical sciences, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Accepted 18 March, 2017
Abstract
Pharmacological therapy is a critical step in the management of individuals with the metabolic syndrome (MetS) when lifestyle modifications cannot achieve the therapeutic goals. However, it has been well- documented that there is no single best therapy other than weight loss, and that treatment should be targeted at individual components of the MetS. The objective of this study was to investigate the treatment of individual components of the MetS in a population-based sample of individuals with clustering MetS components. In a cross-sectional population-based survey, we studied a randomly collected sample of men and women who had participated in the baseline survey of a community-based program in three Central Iranian counties in 2000 to 2001. Demographic data, medical status, and drug history were obtained by questionnaire. We evaluated the association between clustering of the MetS components and pharmacological treatment of cardiovascular risk factors. The most common pharmacologic agents prescribed for individuals with the MetS were beta-blockers (72.8%), followed by lipid-lowering agents (36%) with no significant gender difference. A high level of compliance with drug treatment was noted. Further research is warranted to understand the compliance behavior of patients with the MetS.
Key words: Iran, metabolic syndrome, pharmacological treatment, compliance.