ISSN 2756-3693
African Journal of Biology ISSN 2167-0413 Vol. 2 (9), pp. 183-185, December, 2015. © International Scholars Journals
Short Communication
Analysis on the recurrence rate of pterygium after excision with conjunctival autograft and 5-Fluorouracil
Emeka Linux Ike*, Ubaiangbo Chuks and Micheal I. Oganje
Department of Ophthalmology, Ladoke Akintola University of Technology Teaching Hospital, PMB 5000, Osogbo, Osun State, Nigeria.
E-mail: [email protected]
Accepted 13 November, 2015
Abstract
Pterygium, a conjunctival fibrovascular growth, is a common finding in the tropics. The definitive treatment is excision. The conventional bare sclera technique has a high rate of recurrence. Because of this, different adjuvants have been introduced and are in use to reduce the rate. The purpose of this study is to compare the recurrence rate of primary pterygium after excision with conjunctival autograft and 5-Fluorouracil (5-FU). The overall recurrence rate in the 62 cases was 17.7%. In the group that had 5-FU application, 10 (27.8%) had recurrence while only one of the 26 (3.8%) that had autograft recurred. This difference was statistically significant (Fisher’s exact = 0.018). Primary pterygium excision with conjunctival autograft was superior to 5-FU application.
Key words: 5-Fluorouracil, conjunctival autograft, pterygium recurrence, comparison.