International Journal of Pharmacy and Pharmacology

ISSN 2326-7267

International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 9 (1), pp. 001-004, January, 2020. © International Scholars Journals

Full Length Research Paper

Total phenolics and antioxidant activity of Tridax procumbens Linn.

J. D. Habila1*, I. A. Bello1, A. A. Dzikwi3, H. Musa2 and N. Abubakar2

1Department of Chemistry, Ahmadu Bello University Zaria, Kaduna State, Nigeria.

2Department of Chemistry, Federal College of Education Zaria, Kaduna State, Nigeria.

3Department of Veterinary Public Health and Preventive Medicine, Ahmadu Bello University Zaria, Kaduna State, Nigeria.

Accepted 11 July, 2019

Abstract

Traditional medicinal plant, Tridax procumbens was analyzed for reducing power ability as an antioxidant using the 1,1-diphenyl-2- picrylhydrazyl (DPPH) assay and for total phenolics using the Folin-Ciocalteu method. The results of the analysis show that T. procumbens has a percentage antioxidant activity (AA %) of 96.70 which was observed to be higher than those of gallic (92.92%) and ascorbic acids (94.81%) used as standards. The reductive potential determination shows that T. procumbens has a very significant reductive potential of 0.89 nm at the same concentration with gallic acid whose reductive potential was 0.99 nm. The total phenolic determination shows that T. procumbens has a phenolic content of 12 mg/g GAE. The results of this analysis revealed the fact that plants are rich sources of natural antioxidant.

Key words: Antioxidant activity, DPPH, Folin-Ciocalteu, medicinal plants, Tridax procumbens.