ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 6 (11), pp. 001-005, November, 2017. © International Scholars Journals
Full Length Research Paper
Resistance to erythromycin of Campylobacter jejuni and Campylobacter coli isolated from animals and humans
Z. Tambur1*, B. Miljkovic-Selimovic2, Z. Kulisic 3, D. Mirkovic1, R. Doder1 and Z. Stanimirovic3
1Military Medical Academy, Belgrade, Serbia.
2Medical Faculty, University of Nis, Nis, Serbia.
3Faculty of Veterinary Medicine, University of Belgrade, Belgrade, Serbia.
Accepted 15 July, 2017
Abstract
The sensititivity of thermophilic Campylobacter strains isolated from caecum of broiler chickens as well as caecum and colon of pigs and human stools, were tested against erythromycin. In 16 strains isolated in broiler chickens, resistance rate was found to be 12.50%. Three of 10 strains of Campylobacter jejuni and one of 6 strains of Campylobacter coli isolated from broiler chickens were resistant to erythromycin. In 15 strains of thermophilic Campylobacters isolated from pigs, resistance rate to erythromycin was 40.00%. Resistance was exhibited more often in C. coli (50.00%) as compared to C. jejuni (20.00%). In 24 strains isolated from humans, resistance was demonstrated at the rate of 12.50%. Out of 17 strains of C. jejuni isolated from humans, resistance was exhibited in 17.65% strains. None of 7 strains of C. coli isolated from humans exhibited resistance to erythromycin. Thermophilic campylobacters, especially C. coli isolated from pigs were more resistant to erythromycin than strains isolated from humans and broiler chickens. Therefore, a great attention should be directed to the macrolides monitoring in swine farming in order to prevent resistance in animals and its subsequent spread to human.
Key words: Campylobacter spp., resistance, erythromycin.