ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN 2326-7267 Vol. 12 (1), pp. 001-006, January, 2023. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Antibacterial and antioxidant activities of local seeded banana fruits
Preeti Jain1*, Mahmood Hasan Bhuiyan1, Khondker Rufaka Hossain1 and Sitesh C. Bachar2
1Department of Pharmacy, North South University, Dhaka- 1229, Bangladesh.
2Department of Pharmaceutical Technology, University of Dhaka, Bangladesh.
Accepted 10 August, 2022
Abstract
The antibacterial and antioxidant activities of different parts of local seeded banana fruit were investigated in vitro. Dried peels, pulps and seeds of the fruit were extracted with hexane, ethyl acetate and ethanol. Antibacterial property of the extracts was evaluated against four Gram positive and four Gram negative bacteria using disc diffusion technique. Ethyl acetate and ethanol extract of both pulp and peel exhibited antibacterial activity with zone of inhibition ranging from 9 to 24 mm. On the other hand, only ethyl acetate extract of seeds showed antibacterial activity and the zone of inhibition ranged from 8.5 to 10 mm; interestingly, none of the hexane extracts of the three banana parts exhibited zone of inhibition. Antioxidant activity of the extracts was evaluated by total phenolic content determination and 1,1-diphenyl-2- picrylhydrazyl (DPPH) free radical scavenging assay. Total phenolic content expressed as gallic acid equivalents (GAE) was found to be highest in ethyl acetate extract of banana seed (19.46 mg GAE/g extract) followed by the same extract of banana pulp (15.78 mg GAE/g extract) and peel (11.23 mg GAE/g extract). High free radical scavenging activity was observed with ethyl acetate extracts of banana seed, peel and pulp with an ascorbic acid equivalent antioxidant capacity (AEAC) value of 1238.33, 1011.43 and 588.03 mg AA/ 100 g extract, respectively.
Keywords: Seedy banana, antibacterial, antioxidant, phenolic content.