ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 3 (5), pp. 001-004, December, 2014. © International Scholars Journals
Full Length Research Paper
Anti-inflammatory activity of the venom from samsum ants Pachycondyla sennaarensis
M. A. Dkhil*, A. S. Abdel-Baki, S. Al-Quraishi and M. Al-Khalifa
Zoology Department, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.
Accepted 21 August, 2014
Abstract
Black ants considered as heath hazard problem in many parts of the world. Sting of these ants caused local to systematic reactions and sometimes anaphylaxis. In this study, we proved that the black ant (samsum) venom exerts an anti-inflammatory action on mice model. It was proven that the venom inhibited xylene induced ear swelling in mice with a percentage nearly equal to that of diclofenac. This result was supported by the histological studies which revealed that venom reduced the thickness of the inflamed ears and the cellular infiltration.
Key words: Samsum ant, venom, anti-inflammation, xylene induced ear swelling.