ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 2 (6), pp. 001-004, June, 2011. © International Scholars Journals
Full Length Research Paper
Antibacterial activity of terpenoidal fractions from Anogeissus leiocarpus and Terminalia avicennioides against community acquired infections
A. Mann1, 2*, J. O. Amupitan2, A. O. Oyewale2, J. I. Okogun3 and K. Ibrahim4
1Department of Science Laboratory Technology. The Federal Polytechnic, Bida, P. M. B. 55, Bida, Niger State, Nigeria.
2Department of Chemistry, Ahmadu Bello University Zaria, Kaduna State, Nigeria.
3Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development (NIPRD), P. M. B. 21, Garki – Abuja, Nigeria.
4Department of Microbiology and Biotechnology, National Institute for Pharmaceutical Research and Development (NIPRD), P. M. B. 21, Garki – Abuja, Nigeria.
Accepted 11 April, 2011
Abstract
Terpenoidal fractions were isolated from both Anogeissus leiocarpus (DC) Guill and Perr (Stem) and Terminalia avicennioides Guill and Perr (Root) and assayed against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. The terpenoidal fractions exhibited antimicrobial activities against all the test microorganisms. All test organisms were susceptible to the terpenoidal fractions. The minimum inhibitory concentration ranged between 0.213 and 5.0 µg/ml. The terpenoidal fractions from A. leiocarpus and T. avicennioides could be a potential source of chemotherapeutic agents. The antimicrobial activities of these terpenoidal fractions provide justification for the chemotherapeutic utilization of these plants.
Key words: Anogeissus leiocarpus, Terminalia avicennioides, Terpenoidal fractions, antimicrobial activities.