ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 8 (5), pp. 001-008, May, 2019. © International Scholars Journals
Review
Phytochemistry and pharmacological characteristics of Ruta graveolens L.
*Kamshad Forouhar, Dariush A. Pakraven and Reza Khan
Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Farhangian University, Iran.
Accepted 22 November, 2018
Abstract
Ruta graveolens is known as Rue. R. graveolens extracts and essential oil are important areas in drug development with numerous pharmacological activities in many countries. For a long time R. graveolens has been used in traditional medicines for the relief of pain, eye problems, rheumatism and dermatitis. R. graveolens has recently been shown to have antibacterial, analgesic, anti-inflammatory, antidiabetic and insecticidal activities. Rutin, quercetin, psoralen, methoxypsoralen, rutacridone, rutacridone epoxide and gravacridondiol are phytochemical compounds which are reported from this plant. α-Pinene, limonene and 1,8-cineole were identified as the main monoterpene constituents for R. graveolens essential oil. Due to the easy collection of the plant and being widespread and also remarkable biological activities, this plant has become medicine in many countries especially in Mediterranean region. This article presents comprehensive analyzed information on the botanical, chemical and pharmacological aspects of R. graveolens.
Key words: Ruta graveolens, Rutaceae, pharmacology, phytochemistry.