International Journal of Urology and Nephrology

ISSN 2756-3855

International Journal of Urology and Nephrology ISSN 2756-3855 Vol. 13 (4), pp. 001-006, April, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Review

Arsenic in Water Systems: Ecotoxicological Effects and Their Relevance to Human Health

Gbaruko, B.C.1*, Ana, G.R.E.E.1 and Nwachukwu, J.K.2

1Department of Environmental Health, College of Medicine, University of Ibadan, Nigeria.
2Department of Industrial Chemistry, Faculty of Physical Sciences, Abia State University, Uturu, Nigeria.

Accepted 3 October, 2024

Arsenic is a naturally occurring metalloid element that is found in soil, air and water. Environmental arsenic exists in both organic and inorganic states. Organic arsenicals are generally considered non toxic, whereas inorganic forms are toxic. The most acutely toxic form is arsine gas. Inorganic arsenic exists predominantly in trivalent (As3+) and pentavalent (As5+) forms, where trivalent compounds are more toxic than pentavalent ones. Human activities have also intensified arsenic accumulation in the environment. Organs most susceptible to arsenic toxicity are those involved with absorption, accumulation or excretion, including the skin, circulatory system, gastrointestinal tract, liver and kidney. Arsenic is associated with multiple health effects, including Blackfoot diseases, diabetes, hypertension, peripheral neuropathy and multiple vascular diseases. Other effects include anemia, liver damage, portal cirrhosis, hematopoietic depression, anhydremia, sensory disturbance and weight loss. In addition to acute toxicity, long-term exposure to inorganic arsenic is associated with certain forms of cancer of the skin, lung, colon, bladder, liver and breast. Understanding the ecotoxicological effects of arsenic in the environment is paramount to mitigating its deleterious effects on ecological and human health. This paper is therefore a review of the ecotoxicological effects of arsenic on human and ecological health.

Key words: Arsenic, ecotoxicology, hydrosphere, human health, ecological health.