International Journal of Phytotherapy and Ethnobotany

International Journal of Phytotherapy and Ethnobotany ISSN 4536-1835 Vol. 2 (5), pp. 044-050, July, 2015. © International Scholars Journals

Full Length Research Paper

A study of phytochemical and antimicrobial screening of some medicinal plants in Nigeria

D. Kubmarawa1*, G. A. Ajoku2, N. M. Enwerem3 and D. A. Okorie4

1Department of Chemistry, Federal University of Technology, P. M. B. 2076, Yola, Adamawa State, Nigeria.

2Department of Pharmaceutical Microbiology, National Institute for Pharmaceutical Research and Development Abuja, Nigeria.

3Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria.

4Department of Chemistry, University of Ibadan, Ibadan, Nigeria.

*Corresponding author. E-mail: [email protected]

Accepted 03 March, 2015

Abstract

Ethanolic extracts of 50 plant species were screened for their antimicrobial activity against Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. The results indicated that of the 50 plant extracts, 28 plant extracts inhibited the growth of one or more test pathogens. Four plant extracts showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, saponins, alkaloids, glycosides, flavonoids and essential oils.

Key words: Medicinal plant, antimicrobial activity, phytochemical, ethnomedicinal.

International Journal of Phytotherapy and Ethnobotany ISSN 4536-1835 Vol. 2 (5), pp. 044-050, July, 2015. Available online at www.internationalscholarsjournals.org © International Scholars Journals