ISSN 2326-7267
International Journal of Pharmacy and Pharmacology ISSN: 2326-7267 Vol. 9 (6), pp. 001-003, June, 2020. © International Scholars Journals
Full Length Research Paper
Ethil-cyanoacrylate use for skin closure in patients subjected to laparoscopic cholecystectomy
*Carlos Henrique Marques dos Santos, Lenin Lima Rodrigues, Fernando Bezerra Márcio Matos
*Associate Professor of Federal University of Mato Grosso Do Sul1, Hospital Regional de Mato Grosso do Sul2,3
Accepted 12 April 2020
Abstract
One of the main factors limiting the use of cyanoacrylate is its high cost. Despite the relatively small amount of literature on this subject, we have been able to demonstrate their safe use in skin closure. Objective: To compare the cyanoacrylate adhesive with the usual techniques of skin closure with surgical thread, assessing its final aesthetic effect and possible complications. Materials And Methods: We studied 126 patients from the Department of General Surgery, Hospital Regional de Mato Grosso do Sul in the period from February to October 2009. All patients were randomized immediately before starting the surgery and were divided into two groups: Group 1: 64 patients underwent laparoscopic cholecystectomy and skin closure with surgical thread - Group 2: 62 patients underwent laparoscopic cholecystectomy and skin closure with cyanoacrylate adhesive low cost - Superbonder ®. Results: We evaluated 126 patients, mostly female (N = 113).The mean age was 45 years, ranging between 19 and 83 years. Only group 1 had infection (N = 3) and dehiscence (n = 1) surgical wound. Group 2 had 2 cases of seroma versus 1 patient in group 1. The operative time was shorter in group 2 - on average 80.9 minutes versus 94.14 minutes in group 1. Conclusion: The use of ethyl cyanoacrylate (Superbonder ®) had lower rates of infection and wound dehiscence when compared to with nylon 4-0, in addition to shorter operative time. Costs were higher, but still within the acceptable, which makes this a good choice for adhesive skin closure in laparoscopic surgery elective.
Keywords: cyanoacrylates, laparoscopic cholecystectomy, sutures, skin.