Advanced Journal of Microbiology Research ISSN 2736-1756, Vol. 17 (1), pp. 001-007, January, 2023. © International Scholars Journals

Full Length Research Paper

Acinetobacter baumannii complex and its antibiotics susceptibility in selected hospital's intensive care units at Sana’a city-Yemen

Abdulrahman Ali Mohammed Zabad^1*, Sultan Ayesh Mohammed Saghir², Anwar Kassem Al-Madhagi³, Khaled Abdulkarim Al-Moyed³

¹Department of Medical Microbiology, High Institute for Health Sciences, Sana`a, Yemen

²Department of Medical Analysis, Princess Aisha Bint Al-Hussein College of Nursing and Medical Sciences, Al-Hussein Bin Talal University, Ma`an, Jordan.

³Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Sana`a University, Yemen.

Accepted 06 October, 2022

Abstract

Background and Aim: The main challenge with Acinetobacter baumannii complex (Abc) is its ability to rapidly cause antimicrobial-resistance and ineffective antibiotic therapy. This study is therefore designed to investigate the prevalence rates, infection risk factors and antibiotic susceptibility patterns of Abc in ICUs. Methods: This Cross-Sectional study was carried out for duration of one year in the intensive care units (ICU) units of three hospitals in Sana`a city, Yemen with 280 ICU patients as participants and 80 environmental samples. Results: The prevalence rate of Abc of 7.1% was determined for 280 individual patients admitted in ICU, with 12.9 % in respiratory specimens and 1.4% in blood specimens. All isolated Abc`s became multi-drug resistant over time. Resistance rates were found to be 95% for Piperacillin-Tazobactam, 90% for Imipenem, Cefepime and Ticracillin, 80 % for Amikacin and Doxcycyclin, and 60% for Levofloxacin. However, no resistant isolates were found for Colistin and polymyxin B. The prevalence of Abc in ICUs environment was 8.8% and these isolates were indistinguishable from the clinical isolates using biotyping and antibiotics susceptibilities. Conclusions: Based on its characteristic multi-drug resistance and potential risk to ICU patients, suggestions were offered to prevent nosocomial infections by Abc.

Keywords: Acinetobacter baumannii, Intensive Care Units, antibiotics susceptibility, Yemen