International Journal of Biochemistry and Biotechnology
International Journal of Biochemistry and Biotechnology ISSN 2169-3048 Vol. 12 (1), pp. 001-006, January, 2023. © International Scholars Journals
Full Length Research Paper
Enhanced Phagocytosis and Antibody Production by Tinospora cordifolia - A new dimension in Immunomodulation
M. S. Ranjith1*, A.J.A. Ranjitsingh2, S. Gokul Shankar3, G. S. Vijayalaksmi5, K. Deepa5 and Harcharan Singh Sidhu1
1Microbiology Unit, AIMST University, Kedah, Malaysia.
2Department of Advanced Zoology and Biotechnology, Sri Paramakalyani College, Alwarkurichi, India.
3R and D Center, Cholayil Private Limited, Chennai, India.
4Sri Paramakalyani Center for Environmental Sciences, M.S. University, Tirunelveli, India.
5Anatomy Unit, AIMST University, Kedah, Malaysia.
Accepted 18 December, 2022
Tinospora cordifolia (guduchi) is a widely used shrub in ayurvedic systems of medicine known to possess immunomodulatory properties. In the present study the aqueous extract of T. cordifolia was found to enhance phagocytosis in vitro. The aqueous and ethanolic extracts also induced an increase in antibody production in vivo.
Key words: Immunomodulation, phagocytosis assay, Tinospora cordifolia.
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