International Journal of Public Health and Epidemiology

ISSN 2326-7291

International Journal of Public Health and Epidemiology ISSN: 2326-7291 Vol. 4 (1), pp. 110-114, January, 2015.  © International Scholars Journals

Full length Research paper

Seroprevalence of Zika virus infection specific IgG in Western and North-Western Provinces of Zambia

Olusegun Ayorinde Babaniyi1, Peter Mwaba2,Peter Songolo1*, Mazyanga Lucy Mazaba-Liwewe1,Idah Mweene-Ndumba1,Freddie Masaninga1,Emmanuel Rudatsikira3 andSeterSiziya4

1World Health Organization, Lusaka, Zambia.

2Ministry of Home Affairs, Lusaka, Zambia.

3School of Health Professions, Andrews University, Michigan, United States of America.

4School of Medicine, Copperbelt University, Ndola, Zambia/University of Lusaka, Lusaka, Zambia.

Email: [email protected]

Accepted 28 July, 2014

Abstract 

Zika virus infection is an emerging public health problem in Africa and Asia with potential for global spread. This study was conducted to determine the prevalence and correlates for Zika virus infection in Western and North-Western provinces of Zambia.  A cross sectional study was conducted in which serum samples were tested for IgG and IgM antibodies against Zika virus.  Odds ratio and its 95% confidence interval (CI) were used to determine the magnitude of association. Altogether, 3625 participants were recruited of which 46.7% were male and 9.4% were aged <5 years.  The prevalence of Zika infection was 6.1%.Age below 5 years and living in houses that were sprayed with insecticide residual spray were protective factors against the infection (AOR= 64% (AOR=0.36, 95% CI [0.18, 0.72]) and AOR=19% (AOR=0.81, 95% CI [0.66, 0.99], respectively).  Meanwhile, visiting Angola and living in houses with roofs made of grass were associated with increased risk of infection (AOR=1.42, 95% CI [1.06, 1.90] and AOR=2.03 (95% CI [1.24, 3.33], respectively). Zika virus infection is prevalent in Western and North-Western Provinces of Zambia and should be curtailed through strengthening of diseases surveillance, laboratory diagnostic capacities and clinical management of cases.

Key Words: Arboviruses, zika virus infection, seroprevalence, correlates, Zambia.

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Mazyanga Lucy Mazaba-Liwewe on Google Scholar Mazyanga Lucy Mazaba-Liwewe on Pubmed Idah Mweene-Ndumba on Google Scholar Idah Mweene-Ndumba on Pubmed Peter Mwaba on Google Scholar Peter Mwaba on Pubmed Peter Songolo* on Google Scholar Peter Songolo* on Pubmed Freddie Masaninga on Google Scholar Freddie Masaninga on Pubmed Emmanuel Rudatsikira and Seter Siziya on Google Scholar Emmanuel Rudatsikira and Seter Siziya on Pubmed Olusegun Ayorinde Babaniyi on Google Scholar Olusegun Ayorinde Babaniyi on Pubmed