ISSN 2756-3316
Case Report
African Journal of Medical Case Reports Vol. 2 (2), pp. 022-023, February, 2014. © International Scholars Journals
Case Report
Cytoplasmic anti-neutrophil cytoplasmic antibodies (c-ANCA) in systemic lupus erythematosus: An overlapping syndrome?
El youbi Randa, Mohamed Arrayhani and Tarik sqalli
Department of nephrology at University hospital, Fez, Morocco.
*Corresponding author. E-mail: [email protected] Tel. 00212658932498
Accepted 20 December, 2013
Abstract
Systemic lupus erythematosus (SLE) and small-sized vessel vasculitis are usually two distinguishable autoimmune diseases. We report a case of novo SLE associated with cytoplasmatic antineutrophil cytoplasmatic antibodies (c-ANCA). A 34-year old woman was admitted to our hospital for purpura, weight loss, inflammatory polyarthralgia and nasal stuffiness with advanced renal failure. The investigations have revealed positive immunological test (ANN, anti-DNA and c-ANCA). Renal biopsy showed a diffuse proliferative lupus nephritis (class IV-G (A)) with necrotizing crescentic glomerulonephritis. We have retained the diagnosis of SLE associated to c-ANCA. She has received corticosteroids and cyclophosphamide. The evolution was marked by the occurrence of alveolar hemorrhage that caused her death.
Key words: Cytoplasmic anti-neutrophil cytoplasmic antibodies, systemic lupus erythematosus, overlapping syndrome, alveolar hemorrhage, necrotizing crescentic glomerulonephritis.
El youbi Randa, Mohamed Arrayhani and Tarik sqalli
Page: 22 - 23
Research Article
African Journal of Medical Case Reports Vol. 2 (2), pp. 019-021, February, 2014. © International Scholars Journals
Full Length Research Paper
Salivary gland cystadenocarcinoma of the tongue: A case report and literature review
Mona Mlika1*, Ines Chelly1, Heifa Azouz1, Houda Ouertani2, Ghazi Besbes2, Emna Mnif3, Slim Haouet1, Mohamed Moncef Zitouna1 and Nidhameddine Kchir1
1Department of Pathology, La Rabta Hospital, Bab Saadoun, Tunis, Tunisia.
2Department of Otorhinolaryngology, La Rabta Hospital, Bab Saadoun, Tunis, Tunisia.
3Department of Radiology, La Rabta Hospital, Bab Saadoun, Tunis, Tunisia.
*Corresponding author. Email: [email protected].
Accepted 2 September, 2013
Abstract
Cystadenocarcinoma is a rare salivary gland tumor which commonly arises in the ovary and the appendix. Only 7 cases have been reported in the tongue with 2 cases described as highly malignant. We report a case of cystadenocarcinoma of the base of the tongue in a 79-year-old man who presented with goiter and dysphagia. Physical examination showed a mass of the tongue. Treatment consisted in a partial glossectomy. The patient was free of recurrences after one year of follow up. Cystadenocarcinoma of the tongue is a very rare tumor on which diagnosis is based on histological findings. The treatment is based on surgical excision. These tumours are reported to have a good prognosis but some cases have been described reported to recur even after many years of follow up.
Key words: Cystadenocarcinoma, base of the tongue.
Mohamed Moncef Zitouna and Nidhameddine Kchir, Heifa Azouz, Emna Mnif, Ghazi Besbes, Slim Haouet, Mona Mlika*, Ines Chelly, Houda Ouertani
Page: 19 - 21
Short Communication
African Journal of Medical Case Reports Vol. 1 (1), pp. 001-003, December, 2013. © International Scholars Journals
Short Communication
Chronic viral hepatitis and their relation to ABO blood groups and rhesus (Rh) factor
Alireza Emami Naeini*, Mojtaba Rostami and Sahar Emami Naeini
Department of Infectious and Tropical Diseases, Isfahan Infectious Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
*Corresponding author. E-mail: a_emami [email protected].
Accepted 26 August, 2013
Abstract
ABO blood groups have shown some association with various diseases. Although there are small studies in literature about association between ABO blood groups and chronic viral hepatitis, only few studies found relation between fibrosis severity in chronic viral hepatitis C (CVHC) and ABO blood groups. The aim of this survey is to determine the frequency of different blood groups and Rh (Rhesus) factor in chronic viral hepatitis B (CVHB) and C, to find out if such a host factor may play a role in trend of these viral infections. This is a case control study on patients with CVHB and CVHC referring to infectious diseases research center, Isfahan, Iran and healthy blood donors (HBDs) referring to Isfahan blood bank were selected as control during April 2003 and April 2007. 170 cases with chronic viral hepatitis (130 CVHB and 40 CVHC) and 680 cases of healthy blood donor enrolled in this study. Statistical analyses were performed using SPSS v. 11.0.1 using χ²test. Distribution of blood groups and Rh in CVHB were as the following: Group A, 42 (32.3%), B, 30 (23.1%), AB, 10 (7.7%), O, 48 (36.9%). 115 (88.46%) were Rh positive and 15 cases (11.54%) Rh negative. In CVHC 10 (25%) cases were blood group A,B 14 (35%) cases group B another 14 (35%) case were AB and 2 cases (5%) group B, out of them 37 (92.5%) were Rh positive and remaining 3 (7.5%) were Rh negative. In healthy blood donors 212 (31%) were group A,183 group B (26.8%), 66 group AB (9.7%) and 222 (32.5%) group B. Positive Rh found in 611 individuals (89.45%) and Rh negative 72 (10.55%). Comparing relative frequency of ABO blood groups and Rh between cases of chronic viral hepatitis and control blood donors, there was no significant difference between blood groups (p > 0.5) or Rh (p >0.5) with chronic viral hepatitis.
Key words: Chronic viral hepatitis, blood groups, rhesus (Rh) factor, liver fibrosis.
Alireza Emami Naeini*, Mojtaba Rostami and Sahar Emami Naeini
Page: 1 - 3