African Journal of Medicine and Surgery

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 13 (1), pp. 001-004, January, 2026. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Frequency and Types of Bacteremia Post-Dental Extraction at UBTH, Benin City

Enabulele, O. I.*, Aluyi, H. S. A, and Omokao, O.

Department of Microbiology, Faculty of Life Sciences, University of Benin, Benin City, Edo State, Nigeria.

Accepted 6 October, 2025

170 patients attending the Oral and Maxillofacial Surgery Clinic of the University of Benin Teaching Hospital, Benin City, Nigeria, were screened bacteriologically, to determine the prevalence of bacteraemia following dental extraction procedures. 5 ml of blood was collected from each patient before and after the extraction. Post-operative bacteraemia occurred in 55 (32.4%) of the 170 patients screened. 61 (78.2%) of the 78 isolates obtained in the survey were facultative anaerobes while 17 (21.8%) were obligate anaerobes. Amongst the facultative anaerobes, the most frequently isolated bacterial genus was Staphylococcus (19, 24.4%) followed by Streptococcus spp. (16, 20.5%) and α- haemolytic Streptococcus spp. (10, 12.8%). Bacteriodes spp. (8, 10.3%) was the most frequently isolated anaerobe followed by Peptostreptococcus spp. (5, 6.4%) and clostridium spp. (4, 5.16%). The occurrence of bacteriaemia increased with duration of extraction and number of teeth extracted. It also occurred more frequently when teeth were extracted because of inflammatory dental disease.

Key words: Bacteraemia following dental extraction.
 

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 13 (1), pp. 001-005, January, 2026. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Safety of Antibacterial Dressing Spray for Oral Squamous Cell Carcinoma Wounds

Yizhou Zeng¹, Runzhi Deng¹*, Barry, H.S. Yeung2, Wings T.Y. Loo3, Mary N.B. Cheung3, J.P. Chen3, Bingrong Zhou1, Yifu Fu1, Lanzhu Huang1, Mingxing Lu1 and Min Wang⁴

¹Department of Oral Maxillofacial Surgery, Nanjing Stomatological Hospital, Nanjing, China.
²Department of Microbiology, Immunology and Molecular Genetics, the University of California Los Angeles, USA.
³School of Chinese Medicine, the University of Hong Kong, Hong Kong.
⁴Department of Prosthodontics, West China College of Stomatology, University of Sichuan, Chengdu, P.R. China.

Accepted 8 October, 2025

This study investigates the effects on the prevention of oral infection after operation in oral region by using an antibacterial dressing spray (JUC spray). 60 patients diagnosed with grade 1 and 2 of oral squamous cell cancinoma, and the conservation surgery had applied to them under general anesthesia. Half of these patients were treated with JUC and the rest accepted traditional method. The complete blood picture (CBP) and the growth of bacteria in the wound were analyzed. The average wound healing time in JUC group was significantly shorter than that in the control group. The amount of bacteria presented in wound was lower in JUC group than that in the traditional group. There was no significant difference between the CBP of the two groups. The JUC antibacterial dressing spray, after spraying on the surface of the wound formed a layer of physically antibacterial molecular film to prevent the growth of bacteria and effectively reduced the average wound healing time.

Key words: Antibacterial dressing spray, oral squamous cell cancinoma, wound healing, infection.

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 12 (1), pp. 001-005, January, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Investigating the Role of DLAD Mutations in Age-Related Nuclear Cataract: Findings of No Mutation Presence

Nitza Goldenberg-Cohen^1,5,6*, Bat Chen R. Avraham-Lubin^1, Dorina Calles^1, Olga Dratviman-Storobinsky^1, Rita Ehrlich^4, Boris Paritiansky^4, Yoram Cohen³ and Dov Weinberger^4,6

¹The Krieger Eye Research Laboratory, Felsenstein Medical Research Center, Petah Tiqwa, Israel. ²The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Tel Aviv, Israel. ³Sheba Cancer Research Center, Sheba Medical Center, Tel Hashomer, Israel. ⁴Department of Ophthalmology, Rabin Medical Center, Petach Tiqwa, Israel. ⁵Pediatric Unit, Rabin Medical Center, Petach Tiqwa, Israel. ⁶Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Accepted 22 November, 2024

Abstract

DNase II like acid DNase (DNase IIβ, DLAD) is expressed in human and murine cells in the lens. Studies in mice have reported that abnormal degeneration of cellular organelles by DLAD reduced lens transparency and that the DLAD gene may be involved in cataract formation. The aim of the present study was to search for possible genetic alterations in the DLAD gene in human senile cataract. Anterior lens capsule material was collected during surgery from 55 patients with senile cataract, with or without a subcapsular component. Total DNA was extracted, amplified by polymerase chain reaction and sequenced for exon 3 (n = 51) exon 4 (n = 40) and all 6 exons of the DLAD gene (n = 27). No mutation was found. There were genomic polymorphisms in all exons except 3 and 4. Nonsynonymous genomic polymorphisms were detected in exon 1 (rs738573) and exon 2 (rs3754274) and synonymous polymorphisms were detected in exon 5 (rs7511984) and exon 6 (rs3768250). In contrast to findings in mice, based on the limited samples analyzed, this study suggests that human age-related nuclear cataract is not associated with DLAD mutations.

Key words: DNAase II like acid DNAase- DNAse IIβ- DLAD- senile cataract-nuclear cataract.

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 12 (1), pp. 001-004, January, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

A Clinical Study on CT-Guided Ozone Blowing and Fumigation Therapy for Chronic Refractory Skin Sinus and Ulcer Treatment

Meng-Qi Wei^1, Jian-Shou Zhou^1, Hai-Tao Liu^2, Yuan Yuan^1, Jun-Qing Xu^1, Yong Yang^1, Jin-Song Zhang^1, Yong Peng^1* and Yi Huan^1*

¹Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi’an, China.
²Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an, China.

Accepted 15 October, 2024

Abstract

The purpose of this article is to investigate the clinical effect of CT-guided ozone-blowing and fumigation in the treatment of chronic refractory cutaneous sinus and ulcer. Twenty-six cases of chronic refractory sinuses and ulcers caused by different diseases were retrospectively analyzed in our study. After sterilization, all patients were scanned by computed tomography and the sinuses and ulcers pre-located by CT were treated by O3-blowing and fumigation. Twenty-one patients treated with traditional surgery were randomly assigned into control group. A total number of 15 patients were completely cured in 45 days after receiving CT-guided ozone-blowing fumigation treatment. Four patients exhibited markedly therapeutic effects and three cases showed improvement. The effective ratio was 85%. In control group, seven patients were completely cured in 45 days after being treated by traditional surgery. Four patients exhibited markedly therapeutic effects and five cases showed improvement. An obvious statistical difference exists between two groups. Application of CT-guided O3-blowing and fumigation therapy is an effective approach in the treatment of chronic refractory cutaneous ulcer and sinus with shorter therapeutic duration, less suffering, better curative effect and less adverse effect.

Key words: Computed tomography, ozone, blowing, fumigation, sinus, ulcer.
 

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 11 (11), pp. 001-004, November, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Case Report

A Rare Presentation of Ovarian Lymphoma with Cerebral Leptomeningeal Metastasis: Clinical Insights and Treatment Outcomes

Nejmi Kiymaz¹*, Nebi Yilmaz¹, Mustafa Kösem², Taner Yazici¹, Suleyman Alici³ and Abdulbaki Kozan¹

¹Department of Neurosurgery, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
²Department of Pathology, University of Yuzuncu Yil, School of Medicine, Van, Turkey.
³Department of Medical Onkology, University of Yuzuncu Yil, School of Medicine, Van, Turkey.

Accepted 13 January, 2024

Abstract

A 38 years old female patient is presented who applied to our neurosurgery clinic due to symptoms such as headache, ataxia, vertigo, vomiting and complaints related to a mass at the back side of her head. The examination of cranial magnetic resonance imaging (MRI) of the patient displayed a mass which obliterates the transverse sinus and extends from the scalp to the epidural space at a certain distance and to the occipital zone. The result of the biopsy report revealed an infiltration of malign lymphoma. The patient received cyclophosphamide, adriablastine, vincristine and prednisolone for 1 - 5 days, at 21 days interval and as 6 cures. A complete response was obtained at the end of the 3rd cure. The patient was orientated for radiotherapy at the end of the sixth cure. This case is a rarely seen ovarian lymphoma and constitutes a sample for cerebral leptomeningeal metastasis which is a very rare condition.

Key words: Cerebral leptomeningeal metastasis, primary ovarian lymphoma.

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 11 (11), pp. 001-005, November, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Case Report 

Prolonged Survival Outcomes in Two Cases of Metastatic Leiomyosarcoma of the Uterine Corpus

S.    A. Adewuyi¹*, M. S. Zayyan^2, P. I. Onwuhafua², M. O. A. Samaila³, A. H. Rafindadi³ and A. O. Oguntayo²

¹Radiotherapy and Oncology Department, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.
²Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.
³Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.

Accepted 27 January, 2024

Abstract

Leiomyosarcoma of the uterus is relatively uncommon in Ahmadu Bello University Teaching Hospital, Zaria – Nigeria and generally has a poor prognosis. A report of palliative treatment for invasive leiomyosarcoma of the uterine corpus with pulmonary metastases in 2 women is presented. Both patients presented with advanced bulky locoregional and metastatic disease. The patients had palliative care using multimodality approach with surgery, chemotherapy and radiotherapy. 2 years after treatment, the patients were alive without evidence of locoregional disease, with one patient having residual pulmonary metastasis. Despite evidence of metastasis, it is possible to have long survival, effective palliative care and improvement in quality of life with multimodality and multidisciplinary collaboration.

Key words: Leiomyosarcoma, uterine corpus, pulmonary metastasis.