ISSN 2167-0404
Case Report
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 5 (5), pp. 227-228, June, 2015. © International Scholars Journals
Case Report
Rare causes of tympanic membrane perforation: A case study of a 26-years old lady
Akporine W. Stephanine
Department of Otolaryngology, Delta State University Abraka, Nigeria.
E-mail: [email protected]
Accepted 18 May, 2015
Abstract
This is a case report of a 26 – year old lady who presented in the Accident and Emergency Department of our hospital with complaints of sudden onset of right otalgia, tinnitus and loss of hearing which she claimed started at about 12:30 h after vigorous kissing incident. The tympanic membrane was ruptured. She was managed conservatively with oral antibiotics with spontaneous and complete healing of the perforated tympanic membrane within one month of follow-up. It was shown that ear kissing can lead to auditory injury and loss of hearing and so kissing should be made as gentle as possible in all circumstances.
Key words: Unusual cause, kissing, acute tympanic membrane perforation.
Akporine W. Stephanine
Page: 227 - 228
Research Article
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 5 (5), pp. 224-226, June, 2015. © International Scholars Journals
Full Length Research Paper
Clinical physiognomies of the benign paroxysmal position vertigo associated with sudden sensorineural
Liu Chi Jialu, Feng Keqiang and Justin Minhong
Department of Epidemiology and Biostatistics, Huazhong Agricultural University, Wuhan, China.
E-mail: [email protected]
Accepted 28 May, 2015
Abstract
To explore the clinical characteristics of the benign paroxysmal positional vertigo (BPPV) associated with sudden sensorineural hearing loss (SSHL) (through retrospective analysis of 19 cases from June 2008 to June 2010) and improve the diagnosis and treatment. Nineteen cases (7 male and 12 female, aged 46 to 68 years old) of BPPV associated with SSHL from June 2008 to June 2010 were retrospectively analyzed. All the patients were diagnosed SSHL by history and pure tone threshold test. Positional paroxysmal vertigo was diagnosed by Hallpike test or roll test. Epley maneuver or Barbecue roll maneuver were used to treat according to the type of BPPV, and the efficacy was evaluated by symptom and Hallpike test. 63.2% cases were female patients in the study; BPPV occurred after SSHL in all of the cases (all in the hearing loss ears), of which 15 cases were posterior semicircular canal lithiasis and 4 cases were horizontal semicircula canal lithiasis (only 1 case was cupula lithiasis); 15 out of 19 patients had BPPV within 2 weeks after SSHL; BPPV was cured in all cases after several times of posture treatments. BPPV can result from SSHL. A possible mechanism may be the inner ear circulation disorder or virus infection that lead to otolith falling off. Most cases of BPPV occurred in the posterior semicircular canal of the diseased ear. Otolith reposition is an effective treatment for BPPV secondary to SSHL.
Key words: Benign paroxysmal positional vertigo, sudden sensorineural hearing loss, otolith.
Liu Chi Jialu, Feng Keqiang and Justin Minhong
Page: 224 - 226
Research Article
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 5 (4), pp. 215-223, May, 2015. © International Scholars Journals
Full Length Research Paper
Nasal irrigation mechanism against influenza and non-Influenza viral upper respiratory tract infection
Liu Chi Jialu
Department of Epidemiology and Biostatistics, Huazhong Agricultural University, Wuhan, China.
E-mail: [email protected]
Accepted 15 February, 2011
Abstract
To investigate if nasal irrigation could impact the severity and duration of viral URTI. 22 patients with new onset non-influenza URTI were randomized to Control (Control, N=12) or Nasal Irrigation Group [NI-Flu (-), N=10], and 8 patients with new onset influenza URTI were assigned to Nasal Irrigation Group [NI-Flu (+), N=8]. Patients in control were treated with standard of care, those in Nasal Irrigation Groups performed nasal irrigation three times a day. URTI scores were determined at Day 1, 4 and 8 visits. Influenza virus antigen and soluble intercellular adhesion molecule -1 in nasal secretions were measured at each visit. Clinical symptoms and signs of URTI were significantly improved for patients in both Nasal Irrigation Groups as compared to Control on Day 4 and 8. Patients with positive influenza virus antigen initially become negative on Day 4 and 8 after daily nasal irrigation. Soluble intercellular adhesion molecule -1 concentration in nasal secretion was significantly reduced on Day 4 and 8 in the Nasal Irrigation Groups as compared to Control. Nasal irrigation 3 times a day reduced the severity and shortened the duration of viral URTI, probably in part by removing viruses and inflammatory mediators from and inhibiting viral replication in the nasal cavities.
Key words: Influenza, viral infection, influenza virus antigen, nasal irrigation, anti-backwash, soluble intercellular adhesion molecule -1.
Liu Chi Jialu
Page: 215 - 223
Research Article
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 3 (3), pp. 207-209, April, 2015. © International Scholars Journals
Full Length Research Paper
Analyses of Cu and Zn in serum of sickle cell disease patients in Jos
1Bot Y.S, 2Benjamin A, 1Nyango D.Y, 1Ventmack D.T, 1Eunice C.B, 3Etukudu N.S, 3Obeta M.U
1Department of Chemical Pathology, Plateau Specialist Hospital, Jos, Nigeria.
2Department of Paediatrics, Bingham University Teaching Hospital, Jos, Nigeria.
3Federal School of Medical Laboratory Technology (Science), Jos, Nigeria.
*Corresponding Author. Email: [email protected]
Accepted 02 October, 2013
Abstract
Levels of Cu and Zn in the serum was assessed in a total of one hundred and four (104) subjects comprising of sixty-eight (68) sickle cell disease (SCD) patients attending SCD clinics in Bingham University Teaching Hospital (BUTH), Jos University Teaching Hospital (JUTH) and Plateau Specialist Hospital all in Plateau State, Nigeria and thirty-six (36) age and sex matched apparently healthy control subjects. Blood samples collected from participants were analyzed for Zinc and Copper using spectrophotometry techniques as described by (Yamashita et al., 1989). The mean serum level of Zinc and Copper in sickle cell disease patients was 22.43±13.33 and 109.96±103.96 µmol/L respectively. While serum Zinc levels was significantly lower (P< 0.05), Serum Copper level was significantly higher (P<0.05) in sickle cell disease patients when compared with apparently healthy control. Serum Zinc and Copper levels was not age and sex dependent, as similar pattern of the metal was observed in both male and female SCD patients. Conclusively, the assessment of trace element levels particularly Zinc is vital in the management of SCD. Therefore, the use of zinc supplementation in SCD is strongly advocated.
Key words: Sickle cell disease, copper, zinc, genetic, patient.
Bot YS, Etukudu NS and Obeta MU, Ventmack DT, Nyango DY, Eunice CB, Benjamin A
Page: 207 - 209
Research Article
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 3 (2), pp. 202-206, March, 2015. © International Scholars Journals
Full Length Research Paper
Validation of a quality of life scale for asthmatic patients
Aurora Tapia-Díaz1*, Guadalupe Fabián-San Miguel2, Javier Falcón-Pulido1, Ignacio Páramo-Ramírez1 and Rocío Chapela-Mendoza1
1Asthma Clinic National Institute of Respiratory Diseases (Instituto Nacional de Chapela-Mendoza Respiratorias-INER)
2Metabolic Syndrome Clinic, National Institute of Respiratory Diseases (Instituto Nacional de Enfermedades Respiratorias-INER).
*Corresponding author E-mail: [email protected]. Tel: 52(55)54871704
Accepted 18 March, 2013
Abstract
Exacerbations of asthma reduce the quality of life of people with asthma, and obesity increases the frequency and severity of such exacerbations. Method: The present study was a cross-sectional study. We designed, tested and validated a Likert-type scale to evaluate quality of life from clinical, epidemiological, and public health perspectives. The scale was built on the basis of four theoretical dimensions: physical fitness, clinical condition, emotional condition and economic impact. Results: The quality of life scale had a Cronbach α of 0.8395; one factor with nine variables explored the impact of treatment and medical costs on patients and their clinical condition and physical fitness. Several correlations with the quality of life score were statistically significant, including the frequency of inhaler use (r=0.333; p=0.003), the number of attacks in the last year (r=-0.324; p=0.005) and the thickness of the subcutaneous adipose panicle (r=-0.376; p=0.003). Two variables associated with obesity explained the scale scores: breathlessness and the number of exacerbations in the last year (R2=0.258; p=0.001). Conclusion: We presented a valid, accurate scale that measures the economic impact and lack of control on the quality of life for persons with asthma. Anti-inflammatory alternatives and physical fitness programmes for obese or overweight asthmatic patients should be developed.
Keywords: Quality of life, obesity, asthma, reliability and validity, control.
Ignacio Páramo-RamÃrez and RocÃo Chapela-Mendoza, Javier Falcón-Pulido, Aurora Tapia-DÃaz*, Guadalupe Fabián-San Miguel
Page: 202 - 206
Research Article
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 5 (3), pp. 210-214, April, 2015. © International Scholars Journals
Full Length Research Paper
Comparative microbial evaluation of two edible seafood P. palludosa (apple snail) and E. radiata (clam) to ascertain their consumption safety
Bassey S. C., 1Ofem O. E., Essien N. M. and M. U. Eteng
1Department of Physiology, College of Medical Sciences, University of Calabar, Nigeria.
Department of Biochemistry, College of Medical Sciences, University of Calabar, Nigeria.
*Corresponding author: E-mail: [email protected]
Accepted 8 July, 2014
Abstract
Microbial evaluation of two edible seafood, Pomecia palludosa (apple snail) and Ergeria radiate (clam) were undertaking in this study to ascertain its consumption safety. These sea-food were processed as either fresh sun-dried or cooked oven-dried samples. Results revealed thatthe bacteria loadin fresh samples of E. Radiate (2.20 x 106 - TNT CFU/ml) was significantly (p<0.05) higher compared with P. palludosa (6.10 x 103 - 3.30 x 108 CFU/ml). The coliform count was also significantly (p<0.05) higher in E. Radiate (4-10 coliform/100ml) than in P. palludosa (3-6 coliform/100ml). Cooking significantly (p<0.05) reduced the bacteria load and coliforms in both samples. In P. palludosa, a total of 26 bacteria were isolated: Staphylococcus aureus and Streptococcus pneumonia were most frequent, a total of 20 bacteria were isolated from E. radiata, Vibro spp. and E. colibeing most frequent.The three fungi isolates from freshE. Radiate and P. Palludosa were completely eliminated by cooking. In conclusion, fresh samples of clam and apple snail contain huge microbial load, hence adequate processing and proper cooking is needed before they are consumed.Nevertheless, the vast microbial loads in these species of sea-food could serve as a ready source of microbes in some processing industries.
Key words: P. palludosa, E. radiata, bacteria, fungi, coliforms.
Ofem O. E., Essien N. M. and M. U. Eteng, Bassey S. C.
Page: 210 - 214