International Journal of Medicine and Medical Sciences

International Journal of Medicine and Medical Sciences ISSN: 2167-0447 Vol. 2 (4), pp.103-107, May, 2012. © International Scholars Journals

Full Length Research Paper

Lymphocyte subsets reference values for healthy adults in Togo

Irenée M. Kueviakoe, Akuété Y Ségbéna, Michele Imbert, Mireille David, and  Anne Plonquet

 ¹ MD, Hematology Laboratory, Campus Teaching Hospital, Lome-Togo

² MD, Hematology Laboratory, Campus Teaching Hospital, Lome-Togo

³ MD, Hematology Laboratory, Henri Mondor Hospital, Creteil-France

⁴ MD, Immunology Laboratory, Lome Teaching Hospital, Lome-Togo

⁵ MD PhD, Immunology Laboratory, Henri Mondor Hospital, Lome-Togo

*Corresponding Author’s  E-mail: [email protected]

Received February 5, 2012; Accepted May 23, 2012

 Abstract

The aim of this study was to establish the lymphocyte subsets reference values for healthy adults in Togo. A total of 139 subjects 5(100 males, 39 females) with hematological normal ranges were selected among 1349 voluntary blood donors who were otherwise included in a parallel study to establish the hematological reference values in Togo. All of them were negative for HIV, HBV, HCV infections and malaria. The dual-platform method was used to perform lymphocyte subsets counts. Reference ranges by gender (males vs females) were as follows: total T-lymphocytes (1071-2850 cells/µl vs 1185-2600 cells/µl), CD4-lymphocytes (595-1750 cells/µl vs 675-1650 cells/µl), CD8-lymphocytes (420-1300 cells/µl vs 450-1100 cells/µl), B-lymphocytes (160-558 cells/µl vs 153-700 cells/µl) and NK-lymphocytes (114-560 cells/µl vs 105-550 cells/µl). The range of the CD4:CD8 ratio was 0.9-2.1 in males and 1.1-2.3 in females. The CD8 cells count was lower and CD4:CD8 ratio was higher in females than in males. The B-lymphocyte count was higher than the NK-lymphocyte count unlike some literature data.

Key words: lymphocyte subsets, reference values, healthy adults, Togo

International Journal of Medicine and Medical Sciences Vol. 2 (5), pp.101-102, May, 2012. ISSN: 2167-0404 © International Scholars Journals

Case Report

Giant benign prostatic hyperplasia with large bladder stones

Ali Asghar Ketabchi

Physiology Research Center Urology Department, Bahonar Hospital Kerman Iran

Received December 6, 2011; Accepted May 16, 2012

 Corresponding Author’s E-mail: [email protected]

The giant hyperplasia of the prostate is extremely rare pathology of prostate gland. Here, we report the successful removal of a giant BPH (312 g) with multiple bladder stones in a 75-years-old man with severe LUTS (30 IPSS ) by supra-pubic prostatectomy.

Key Words: Giant BPH , Prostatectomy, Bladder stone

International Journal of Medicine and Medical Sciences  ISSN: 2167-0447 Vol. 2 (4), pp. 086-087, April, 2012. © International Scholars Journals

Case Report 

Adult Jejunojejunal intussusception – submucosal hamartomatous polyp as a lead point 

Rajesh Sisodiya, Rajgopal Shenoy, Akash Gupta, Fousiya Yoonus

Department of Surgery, Kasturba Medical College, Manipal, India.  

*Corresponding Author’s E-mail: [email protected]

Received March 26, 2012; Accepted April 25, 2012

Abstract

Adult jejunojejunal intussusceptions are rare accounting for only 5% of all cases of intussusceptions. They should be ruled out in patients with recurrent upper gastrointestinal obstructive symptoms. Lipomas, polyps, neurofibromas, leiomyomas, hemangiomas, hamartomas  are benign lesions responsible for these cases. We present a 20 year old girl with recurrent pain abdomen, bilious vomiting secondary to jejunojejunal intussusceptions. Key words: intussusceptions, jejunojejunal, adults

International Journal of Medicine and Medical Sciences ISSN: 2167-0447 Vol. 2 (4), pp.088-091  April, 2012. © International Scholars Journals

Full Length Research Paper

Antibiotic Prophylaxis in Joint Arthroplasty: Do we get it right?

¹David Graham, Ian Williams², Benjamin Parkinson³, Nicholas Stewart⁴ and David Cottle⁵

^{1, 2, 3} Department of Orthopaedics, Gold Coast Hospital

⁴ Department of Surgery, Ipswich Hospital

⁵ Department of Orthopaedics, Liverpool Hospital

Received 11 April, 2012; Accepted 28 April, 2012

*Corresponding Author’s E-mail: [email protected]

Abstract

Purpose: The goal of this study was to investigate whether our institution adhered to current guidelines for the use of prophylactic antibiotics in hip and knee arthroplasty.

Type of Study: Retrospective case series.

Methods: Data on the administration of prophylactic antibiotics for 798 consecutive total hip arthroplasty, total knee arthroplasty, and hip hemiarthroplasty procedures were recorded. All primary and revision procedures were included.  This data has been analysed to assess if antibiotic prophylaxis administration has followed the current American Academy of Orthopaedic Surgeons guidelines.

Results: Prophylactic antibiotics were correctly administered in 266 cases (91.4%) of THR, 259 cases (92.5%) of TKR, 148 cases (86%) of hip hemiarthroplasties, 34 cases (82.9%) of revision THR and 13 cases (92.9%) of revision TKR.

Conclusions: The benefit of appropriate prophylactic antibiotic administration in joint arthroplasty is well established and documented in the literature1.  This study demonstrates that 9.8% of patients undergoing hip and knee arthroplasty procedures are not receiving antibiotic prophylaxis as per AAOS guidelines. This highlights that there is scope for improving current practice and demonstrates the need for clinical audit to ensure that best practice is being undertaken.

Level of evidence: Level IV, case series

Key words: prophylactic, infection, arthroplasty, antibiotic, total hip, total knee 

International Journal of Medicine and Medical Sciences ISSN: 2167-0447 Vol. 2 (4), pp.092-096, April, 2012. © International Scholars Journals

Full Length Research Paper

A Survey of Upper Aerodigestive Tract Emergencies Seen in a Nigerian Tertiary Hospital

Onotai L.O and Ibekwe M.U

FWACS, DEPARTMENT OF E.N.T SURGERY UPTH, PORT HARCOURT, NIGERIA.

Received 12 April, 2012; Accepted 28 April, 2012

*Corresponding Author’s E-mail: [email protected]

Abstract

Background: Emergencies of the upper aerodigestive tract are not uncommon in our environment and can be life threatening and challenging to the otolaryngologists.

Objective: To assess the size and distribution of upper aerodigestive emergencies in our setting, to obtain base line data and outline preventive measures.

Patients and methods: It was a retrospective study of patients seen with upper aerodigestive tract emergencies in University of Port Harcourt Teaching Hospital (UPTH) Port Harcourt, Nigeria within the period of January 2004 and December 2010. Patient records were retrieved from the Accident and Emergency (A/E) registers, Children Emergency Ward (CHEW) records, Ear Nose and Throat (ENT) ward registers and theatre registers.  The data analyzed were demographic data, clinical presentations, etiological factors of upper aerodigestive emergencies, complications, treatment and outcome.

 Results: A total of 142 patients presented with upper aerodigestive tract emergencies within the study period out of 4,580 ENT emergencies giving a prevalence of 3.1% of the total number of patients with ENT emergencies.  The total ENT cases seen were 62,400 cases. There were 74 males and 68 females. The age range was 1-65 years with a mean of 22.16 ± 16.25 years. Age group 1-10 years accounted for majority of the cases 54 (38.02%).  Foreign bodies ranked highest as an etiological factor of these emergencies. Difficulty in breathing, odynophagia and dysphagia were the commonest modes of clinical presentation 80 (56.34%). There were 50(35.2%) emergency tracheostomies done and mortality occurred in two patients.

Conclusion: The commonest etiological factor responsible for most of the upper aerodigestive tract emergencies was FB aspiration/ ingestion. The burden of upper aerodigestive tract emergencies in our environment is enormous. Therefore, the A/E department physicians should be well equipped to successfully resuscitate the patients before referring them to otolaryngologists

Key words: Emergencies, Upper aerodigestive tract, Tertiary hospital, Nigeria 

International Journal of Medicine and Medical Sciences ISSN: 2167-0447 Vol. 2 (4), pp.095-099, April, 2012. © International Scholars Journals

Full Length Research Paper

Effect of Nutrition Education on Anthropometric and Blood Glucose Levels of Niddm in Guntur City

Jalaja Kumari .D 

 Faculty, Department of Foods & Nutritional sciences, Acharya Nagarjuna University (A.N.U), Guntur.

Corresponding Author’s E-mail: [email protected]

Received December 05, 2011; Accepted April 26, 2012

Abstract

Sixty Non Insulin Dependent Diabetic subjects in the age group of 40-60 years were selected from hospital of Sri hari Krishna diabetic care centre, Guntur and were surveyed for their nutrient adequacy using “24 hour recall method” for three consecutive days. Nutrition education was imparted to the subjects after assessing their basic knowledge regarding the diet and disease. Nutrition Counselling improved their mean score of diabetic knowledge significantly (P<0.01). The height, weight, body mass index and waist to hip ratio of the subjects were measured before and after nutritional education. A significant decrease in weight (66.45 to 61.20 kg), body mass index (27 to 26.2 kg/m2) and waist to hip ratio (0.89 to 0.85) and fasting blood concentrations of glucose (FBS), HbA1c, total cholesterol, and triglyceride. However, no such improvements were observed in control group. was observed. Significant decrease in the consumption of cereals, milk and milk products, fats and oils, sugar and jaggery whereas increase in the consumption of pulses, green leafy vegetables, root vegetables was found among diabetics after nutrition counseling. The percentage of calories from carbohydrates 59 to 61%, protein 13 to 16% increased and from fat it was decreased to 27 to 22% in the subjects after nutrition counseling. The intake of fiber (39 to 44%) increased while of vitamins and minerals except iron, zinc and niacin were adequate in the subjects after nutrition counseling as compared to ICMR’s recommendations. Therefore it can be concluded that nutrition counselling is an important measure for improving the knowledge and bringing about favourable and significant changes in anthropometry of diabetics.

Keywords:  NIDDM, Prevalence, Nutrition Counseling and Over weight.