International Journal of Medicinal Plants Research

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 15 (1), pp. 001-005, January, 2026. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Herbal Heritage of the Seshachalam Hills: Documenting Indigenous Medicinal Plants and Ethnomedical Practices in Southern India

C. Sudhakar Reddy¹*, K. N. Reddy², E. N. Murthy³ and V. S. Raju³

¹Forestry and Ecology Division, National Remote Sensing Agency, Balanagar, Hyderabad-500 037, India.
²Laila Impex, R and D Centre, Unit-1, Phase-3, Jawahar Autonagar, Vijayawada-520 007, India.
³Department of Botany, Kakatiya University, Warangal, Andhra Pradesh-506 009, India.

Accepted 13 November, 2025

The present study documents the traditional knowledge of medicinal plants that are in use in Seshachalam hill ranges in Cuddapah district, Andhra Pradesh, India. Ethnomedicinal uses of 48 plant species along with botanical name, vernacular name, family and mode of administration are presented. They belong to 44 genera and 30 families. These plants used to cure 32 types of ailments. Most remedies were taken orally, accounting for 78% of medicinal use. Most of the remedies were reported to have been from trees and climber species. The most widely sought after plant parts in the preparation of remedies in the study area are the leaves and root. High number of medicinal plant species available for the treatment of skin diseases and indigestion. The study emphasizes the potentials of the ethnobotanical research and the need for the documentation of traditional knowledge pertaining to the medicinal plant utilization for the greater benefit of mankind.

Key words: Ethnomedicine, medicinal plants, Yanadis, Seshachalam, eastern Ghats.
 

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 14 (10), pp. 001-010, October, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Antiplasmodial in vitro and in vivo activities of crude extracts from Ozoroa obovata (Oliv) R.Fern. &A. Fern collected in Burkina Faso

Aboubakar Soma^1,2, *, Mariam Ouedraogo^1,2,3, Bonewendé Mohamed Belemlilga¹, Abdel Aziz Mintoumba^1,2, Farida Carelle Ariane Kaboré^2,4, Tiami Jonas Coulibaly^1,3, Abdoul Laurent Gilchrist Boly¹, Harouna Soré², Souleymane Compaoré¹, Nicolas Ouedraogo², Guillaume Sanou², Noufou Ouedraogo¹, Maminata Traoré-Coulibaly¹ and Aristide Traoré¹

¹Laboratoire de Recherche-Développement de Phytomédicaments et Médicaments (LR-D/PM), Institut de Recherche en Sciences de la Santé (IRSS/CNRST), Ouagadougou, Burkina Faso
²Laboratoire de Pharmacognosie, Centre National de Recherche et de Formation sur le Paludisme (CNRFP), Institut National de Santé Publique (INSP), Ouagadougou, Burkina Faso
³Laboratoire de Développement du Médicament (LADME), Centre de Formation, de Recherche et d’Expertises en Sciences du Médicament (CEA-CFOREM), École Doctorale Sciences de la Santé (ED2S), Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
⁴Laboratoire de Biologie Moléculaire de Génétique (LABIOGENE), Département de Biochimie et Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso.

Abstract

Received 22 September, 2025; Revised 02 October, 2025; Accepted 03 October, 2025; Published 21 October, 2025

Malaria remains the main health concern in sub-Saharan Africa. This study aimed to evaluate the in vitro and in vivo antiplasmodial activities of Ozoroa obovata extracts, a plant traditionally used to treat malaria in Burkina Faso. The macerate extracts were freeze-dried, and TLC analysis was used to analyze the phytochemical compounds. The in vitro antiplasmodial activity was evaluated using the Plasmodium lactate dehydrogenase (pLDH) method. The in vivo antimalarial activity of the extract was evaluated in mice infected with Plasmodium berghei using the Peters’ 4-day suppressive test. Thin-layer chromatography (TLC) analysis revealed the presence of flavonoids, sterols, triterpenes and tannins in both the aqueous and hydroethanolic extracts. The IC50 of the aqueous extracts were 58.59 ± 9.05μg/ml against the 3D7 and 56.14 ± 7.84 μg/ml against NF54 strains. The hydro-ethanolic extracts shown the IC50 of 161.10 ± 12.51μg/ml against the 3D7 and 76.28 ± 3.20μg/ml against NF54 strains. The percentages of reduction in parasitemia with the aqueous extract were 2.5%, 54.00%, and 92.00% at 100mg/kg, 250mg/kg, and 500mg/kg body weight, respectively. The hydroethanolic extract showed reductions of 7.00, 65.00, and 83.75% for the respective doses 100mg/kg, 250mg/kg and 500mg/kg body weight. These activities shown could justify the using of O.obovata in traditional medicine to treat malaria.

Keywords: Ozoroa obovata (Oliv) R.Fern. &A. Fern, Malaria, Antiplasmodial activity, Burkina Faso, In vitro, in vivo.
 

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 14 (10), pp. 001-005, October, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Antimicrobial Potential and Chemical Profiling of Chrysocoma ciliata L. Leaf Essential Oil

A. J. Afolayan* and A. O. T. Ashafa

Department of Botany, University of Fort Hare, Alice 5700, South Africa.

Accepted 29 April, 2025

Chrysocoma ciliata L. is one of the South African medicinal plants used for the management of pains, stomach and menstrual disorders by the people of the Eastern Cape. The essential oil extracted from the leaves of the plant through hydrodistillation yielded 1.20% (volume/fresh weight). A total of 37 compounds were identified, constituting 85.28% of the total oil composition. The major components of the oil were the monoterpenes (a-pinene, 7.87%; β-pinene, 42.94%; myrcene, 6.13%, cis-ocimene, 7.23%; allo-ocimene, 1.18%) and sesquiterpenes (trans-beta farnesene, 1.49%; germacrene D, 1.82%; bicyclogermacrene, 2.52%; viridiflorol, 7.70%). The oil inhibited both bacteria and fungi species at relatively low concentrations. The 10 bacteria (five gram-positive and five gram-negative) used were inhibited at minimum inhibitory concentration (MIC) range of 0.08 - 10.00 mg/ml. Also, the oil suppressed the growth of four fungi species with inhibition zone ranging from 14.50 - 51.24 mm. The presence of monoterpenes as the major constituents of the essential oil from this herb could be responsible for the notable antimicrobial activity observed in this study. Therefore, the essential oil from C. ciliata could be promising natural product for the development of antimicrobial agents.

Key words: Chrysocoma ciliata, hydrodistillation, essential oil, antimicrobial activity.
 

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 14 (10), pp. 001-007, October, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Antibacterial Activity and Phytochemical Profile of Parkia biglobosa: A Study of Leaf, Stem Bark, and Root Extracts

C. E. Udobi¹* and J. A. Onaolapo²

¹Department of Food Technology, College of Science and Technology, Kaduna Polytechnic, Kaduna, Nigeria.
²Department of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University Zaria, Nigeria.

Accepted 6 August, 2025

Antibacterial evaluation of the methanolic extract and aqueous fractions of the Leaf, Stem Bark and root of the African locust bean tree, Parkia biglobosa was carried out using the agar- well diffusion method. The extracts and their fractions were tested against two gram positive organisms – Staphylococcus aureus ATCC 25923 and Bacillus subtilis NCTC 8326B76 and two gram negative organisms–Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC-27853. Results obtained confirmed a broad spectrum of activity as all the organisms used were inhibited by the extracts and their aqueous fractions at concentrations between 2.5 – 20 mg. Zones of clearing observed against S. aureus were more pronounced, distinct and wider than those against other organisms tested. It was closely followed by P. aeruginosa. Results of the Minimum Inhibitory Concentrations (MIC) test using the aqueous fractions showed that the MIC ranged from 1.562 - 25mg/ml. This confirms the high activity of the aqueous fraction of the methanolic extract of the stem bark (WS) against S. aureus ATCC 25923 and P. aeruginosa ATCC 27853. The WS showed higher activity than the aqueous fraction of the methanolic extract of the leaf (WL) and the aqueous fraction of the methanolic extract of the root (WR). When the extracts were screened for secondary metabolites, tannins, flavonoids and saponins were detected among others. This was further confirmed by the aqueous fractions. These secondary metabolites are most likely responsible for the observed activity of the plant parts. Results obtained in this work justify the medicinal uses to which P. biglobosa parts have been employed traditionally in recipes for infection.

Key words: Antibacterial evaluation, parkia biglobosa, aqueous fraction, minimum inhibitory concentration, secondary metabolite.

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 14 (9), pp. 001-005, September, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper
    
Evaluation changing of essential oil of balm (Melissa officinalis L.) under water deficit stress conditions

Hossein Aliabadi Farahani¹*, Sayed Alireza Valadabadi¹, Jahanfar Daneshian¹ and Mohammad Ali Khalvati²

¹Islamic Azad University of Takestan branch, Iran.
²Department of Plant-Microbe Intraction, German Research Centre for Environment and Health Munich (HelmholtzZentrum Muenchen), Ingolstaedter 1 Neuherberg, Germany.

Accepted 18 July, 2025

An experiment was carried out using a randomized complete block design with 4 replications to study the effect of water deficit stress on essential oil of balm. The factors studied included 5 levels of water deficit stress that were T1 (100% field capacity), T2 (80% field capacity), T3 (60% field capacity), T4 (40% field capacity) and T5 (20% field capacity) respectively. The results showed that water deficit stress significantly affected biological yield, essential oil yield, essential oil %, leaf yield, height of plant, tiller number, stem diameter, stem yield and internode length in P < 0.01. Highest biological yield and height of plant were achieved under T1, highest essential oil yield was achieved under T3 and highest stem diameter and essential oil % were achieved under T5. The results of this experiment showed that essential oil yield was reduced under water deficit stress but essential oil % increased under this condition.

Key words: Water deficit stress, essential oil, balm.
 

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 14 (8), pp. 001-005, August, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals

Full Length Research Paper

Bioactive compounds and antimicrobial efficacy of African myrrh (Commiphora africana) root extracts

Akor J. S¹ and Anjorin T. S²*

¹Department of Chemistry, University of Abuja, Nigeria.
²Department of Crop Science, University of Abuja, Nigeria.

Accepted 23 March, 2025

The crude ethanolic extract of Commiphora africana root was partitioned with n-hexane, chloroform; water and 10% aqueous methanol and screened for chemical constituents and antimicrobial activity. The n-hexane fraction, which was the most bio-active was chromatographed on a column silica gel to give a number of purified components. The components from the n-hexane were found to be active against Staphylococcus aureus, Escherichia coli and Candida albicans. S. aureus (ATCC 13709) was susceptible to fractions C1 - 11 giving zonal inhibition of between 1 - 3 mm. Standard antibiotics - amoxillin, chloramphenicol and tetracycline were compared with the extracts in antimicrobial activity.

Key words: Antimicrobial activity, Commiphora africana, phytochemical activity, root extracts.